Environmental microbiology

12

employees

30

publications over the last 5 years

17

projects

Water is our most precious resource – we depend on it for drinking, feeding ourselves, and keeping our ecosystems alive. Protecting and monitoring this vital resource means protecting everyone's well-being and health. But how can we ensure that water flowing through our environment, rivers, and taps remains safe? What can this water teach us about emerging chemical and microbiological threats facing our societies?

A meaningful water quality monitoring framework acts as an early warning system: it allows us to detect epidemics before they explode, identify contamination before it spreads, and protect public health proactively rather than reactively.

Infectious diseases continue to pose serious threats to global public health, despite major progress in medicine, vaccination, and sanitation. The forces shaping their spread are deeply interconnected, reflecting the complexity of our globalized world. The rapid movement of people and goods allows pathogens to travel across continents within hours, turning local outbreaks into international crises. Global changes and climate change further intensify risks by altering ecosystems, expanding the geographical range of vectors carrying infectious diseases, such as mosquitoes. Extreme weather events - heatwaves, floods, and storms - not only cause immediate loss of life but also disrupt communities, public health systems, and ecosystems. Simultaneously, rapid urbanization and population growth, particularly in cities with limited infrastructure, create crowded environments where sanitation and access to clean water are insufficient, facilitating the transmission of waterborne and water-related diseases. Adding to these challenges, antimicrobial resistance represents a growing crisis as the overuse of antibiotics in medicine and agriculture practices has led to strains of bacteria that are increasingly difficult to treat, threatening to undermine decades of medical progress.

The complexity of current health threats demonstrates the fundamental interconnection between human, animal, and environmental health. Biodiversity loss increasing the risk of zoonotic infectious diseases, such as COVID-19, highly pathogenic influenza viruses and emerging infections, crossing from animals to humans, remind us of that new global health emergencies are inevitable. This reality underscores the necessity of adopting a One Health approach that recognizes the intricate relationships between human activities, environmental changes, and disease emergence.

Understanding these global challenges provides the context in which our research group operates, guiding the design of innovative solutions at local, regional, and international levels. Our research directly addresses these interconnected threats by developing early detection systems that can identify microbiological risks before they become public health crises. Through this integrated approach, our research contributes to building resilient monitoring frameworks that serve as critical tools for protecting public health in an increasingly complex and interconnected world

Mission

Building on this context, the mission of the Environmental Microbiology Group is to translate global health threats into concrete research actions and solutions. 

To address these pressing challenges and fill the gaps in current knowledge about these pathogens, we are focusing on two complementary approaches: developing innovative, cost-effective technologies for detection and real-time monitoring, and developing sustainable decontamination technologies to ensure a safe environment for humans, animals and ecosystems.

Beyond research, the group is strongly committed to knowledge transfer and public awareness. Raising understanding of environmental and health risks is seen as essential to prevention, and outreach initiatives are used to engage both citizens and stakeholders. This commitment to sharing knowledge helps make scientific outcomes more impactful and sustainable.

Activities involve both the European and international levels, by strengthening public health capacities in Luxembourg, collaborating across European networks, and engaging in projects that directly involve low- and middle-income countries (LMICs). Many of our outcomes are designed to be scalable and transferable to ensure a broader global impact.

Fully aligned with the LIST missions, the Environmental Microbiology Group is supporting public and private partners (nationally and internationally) in reaching their objectives in terms of positive impact for health and environment as well as economic competitivity and political stability. LIST has been particularly active in bringing together the healthcare and environmental sectors.

Scope of expertise

Based on a 20-year experience in monitoring environment-borne pathogens, the Environmental Microbiology Group develop innovative sensors, monitoring procedures and data treatment to support decision-making at all stages of the water cycle. 

Our work is structured around three observatories:

  • Drinking Water Observatory - to detect microbial contaminants before water reaches the consumer, ensuring safety in treated or treated-from-source water. Strategic points across the drinking water supply network are monitored with the use of sensors that transmit high-resolution data in near-real time.
  • Wastewater-Based Observatory – to monitor infectious viral diseases and the evolution of antimicrobial resistance through wastewater analysis in Luxembourg. By sampling the inlets of 13 wastewater treatment plants, this observatory covers roughly 75 % of the country’s population. Tracking key pathogens, such as SARS-CoV-2 and influenza, provides an early warning of outbreaks. The resulting data are promptly shared with health authorities and the public (microbs.lu).
  • Field Observatory – to monitor potential microbial pathogens, and their toxins in surface water for preventing health risks. Harmful algal blooms, for instance, are tracked using automated, real-time instruments. Hourly images from cameras at key sites and sensor buoys detecting early bloom indicators allow rapid response. This early-warning system provides actionable guidance to protect public health, particularly for recreational water use (see cyanowatch.lu). Vectors of viruses such as West Nile Virus or Chikungunya are monitored to support the surveillance of these emerging pathogens made by the Luxembourg’s Health Directorate.

Started ten years ago with joint projects with LIST experts in Material Sciences, the Environmental Microbiology Group develop and validate decontamination technologies, based on physical, physico-chemical and biological processes.

Our expertise covers:

  • Mitigation, prevention, and decontamination strategies for pathogens and contaminants in water and environmental matrices
  • Physical- and biological-based decontamination methods, tailored to diverse use cases
  • Assessment of antimicrobial and antiviral activity of materials, surfaces, and products
  • Microbial diagnostics, including evaluation of products or technologies with antimicrobial effects

The group also contributes to strengthening capacities through targeted training initiatives. Training activities have been developed as part of the Erasmus+ OneHealthWatch project, and this commitment continues within the European EU-WISH project. These efforts aim to strengthen and improve national capacities for wastewater-based public health surveillance by enhancing knowledge exchange and sharing best practices grounded in scientific evidence.

To apply this expertise in practice, the group relies on a wide range of state-of-the-art tools and facilities and has developed strong expertise in their use. 

These include:

  • Fully equipped biosafety level 2 laboratories
  • Molecular biology platform (qPCR, ddPCR, Next-Generation Sequencing, Bioanalyser, DNA/RNA extraction robots)
  • Cell culture facilities (Culture-based growth and enumeration of environmental bacteria, virus production, anaerobic culture chamber)
  • Cold atmospheric plasma generator
  • Equipment sampling and analyzing microbes in aerosols
  • Platform for study interaction between molecules (protein-protein, protein-nucleic acids, etc.) -> SPRi, CFM
  • Equipment for the development and analysis of aptamers (Selex platform)
  • Microscopy technologies (confocal, epifluo, inverted microscopes, etc...)
  • Field equipment (autosamplers, online monitoring systems, battery, etc...)

This technical capacity allows us to generate high-quality data, ensure robust validation of results, and deliver actionable insights to partners and stakeholders.

In addition to laboratory infrastructure, the team has developed extensive software expertise to support its mission. This includes data analysis and visualization using tools such as R, R Shiny, and Quarto; design of training materials with Articulate 360; and creation of didactic and informative visuals using Adobe Creative Cloud. These skills ensure that scientific results are effectively analyzed, communicated, and shared with both professional and public audiences.

The Environmental Microbiology Group benefits from strong national partnerships and contributes to policy support and decision-making. The team is recognized for its ability to adapt to emerging public health needs and for maintaining a high level of technical expertise across diverse methods. Collaboration plays a central role in our activities, including projects with industrial partners and support for the development and validation of innovative solutions.

Our people

BURNET Jean-Baptiste

Environmental microbiology

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CAUCHIE Henry-Michel

Environmental microbiology

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COLLARD Delphine

Environmental microbiology

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CORVISY Aude

Environmental microbiology

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FAUVEL Blandine

Environmental microbiology

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HOCK Louise

Environmental microbiology

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KHAZALI Nazanin

Environmental microbiology

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KUMPF Cassandre

KUMPF Cassandre

Environmental microbiology

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OGORZALY Leslie

Environmental microbiology

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SETT Arghya

Environmental microbiology

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WALCZAK Cécile

Environmental microbiology

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Our latest projects

SUPERVIR

Establishment of a permanent wastewater surveillance system for key viral pathogens of concern in Luxembourg

PREWAPHARM

Prevent water pollution by pharmaceuticals

APTAVIR

Aptasensors as an emerging and convenient tool to improve the multiplex detection of foodborne viral diseases

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Our latest publications

Immobilization of lignin nano/microparticles on plasma-modified polymer nanofibers

Janů L., Souawda N., Anand R., Duday D., Medalová J., Collard D., Nečas D., Polášková K., Ryšánek P., Thomann J.S., Janůšová M., Zajíčková L.

International Journal of Biological Macromolecules, vol. 343, art. no. 150226, 2026

Integrating AMR surveillance into wastewater monitoring systems in 2025: a position on the implementation of Article 17 of the Urban Wastewater Treatment Directive (UWWTD)

Hock L., Luiken R., Valério E., Vargha M., Vierheilig J., Börjesson S., Pitkänen T., Schmitt H.

Euro Surveillance Bulletin Europeen Sur Les Maladies Transmissibles European Communicable Disease Bulletin, vol. 31, n° 3, 2026

Co-occurrence of memory impairment and fatigue distinguishes post COVID from pandemic-related health effects in the 4-year CON-VINCE cohort study

Martins Conde P., Bulaev D., Rauschenberger A., Ohnmacht J., Fritz J.V., O’Sullivan M.P., Ancien F., Ghosh S., Tsurkalenko O., Kolodkin A., Satagopam V., Vaillant M., Klucken J., Krüger R., Lorentz V., Bocquet V., Lamine S., Mtimet S., Roland O., Kofanova O., Aouali N., Menster M., Alexandre M., Valenti M., Richard I., Nieser G., Marques G., Contesotto G., Neu F., Soboleva E., Meek C., Coimbra C., Gamio C., Schritz A., Mendibide A., Parrish A., Saracino S., Sega R., Theresine M., Ferrari A., Zamboni T., Weibel E., Weber B., Wauters F., Wang X., Walczak C., Vögele C., Vyas M., Verschueren C., Moreno C.V., Esteves D.V., Turner J., Trung N., Trouet J., Trefois C., Toukourou N., Toll S., Thien H., Stute L., Sokolowska K., Snoeck C., Skrozic A., Simon F., Servais J.Y., Seal S., Schweicher A., Schumacher S., Schröder V., Schneider R., Schmitt C., Schmitt M., Sausy A., Satagopam V.P., Santos B., Sandt E., Rump K., Rommes B., Rodriguez A., Remark L., Meyers G.R., Plesseria J.M., Pirard M.F., di Pinto P., Pexaras A., Perquin M., Penny C., Pavelka L., Pauly L., Pauly C., Ollert M., Olesky C., Ogorzaly L., O’Sullivan M.P., Nicolai B., Nguyen T., Neumann M., Mühlschlegel F., Mériaux S., Munsch M., Mousel A.

Scientific Reports, vol. 15, n° 1, art. no. 37381, 2025

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