AUDINOT Jean-Nicolas

About

I am a Group Leader of the Advanced Instrumentation for Nano-Analytics (AINA) team within the Scientific Instrumentation and Process Technology (SIPT) Unit. My work focuses on advancing secondary ion mass spectrometry (SIMS) and developing next-generation instrumentation for high-resolution chemical imaging at the nanoscale. With over 30 years of experience in SIMS, including NanoSIMS and magnetic sector instruments, I specialize in ion–matter interactions and the development of advanced analytical workflows. These workflows combine SIMS with complementary techniques such as electron microscopy, atomic force microscopy, and correlative approaches, enabling isotopic tracing, as well as 2D and 3D chemical imaging, to characterize materials, energy systems, and environmental samples with high spatial and chemical resolution. I develop and promote FIB-SIMS platforms in close collaboration with industrial partners, supporting multi-scale, correlative analyses across a wide range of applications, including energy materials, batteries, photovoltaics, soils, nanoplastics, and persistent contaminants such as PFAS. My work also explores the integration of artificial intelligence and machine learning to improve data interpretation, automate workflows, and enhance instrument performance. I am passionate about translating these advanced analytical capabilities into solutions for pressing societal challenges, from sustainable energy technologies to environmental protection. I am also dedicated to mentoring early-career scientists and fostering collaborations across academia and industry, ensuring that cutting-edge analytical science continues to drive innovation and impact.

Mission

Head of group - Advanced Instrumentation for Nano-Analytics (AINA)

Skills and expertise

• Surface Analysis
• Secondary Ion Mass Spectrometry
• Focused Ion Beams
• Ion & Electron Microscopy
• Materials characterization

Key collaborations

• CEA-LITEN
• Université Nantes (IMN)
• Technische Universität München (TUM, Munich)
• Toxalim /INRAE (Toulouse)
• Raith

Projects

• microPLAstox: Oral exposure to bio-based versus conventional nanoplastics: unravelling health hazards in humans using hand-in-hand in vitro gut models and multiscale analytics
• Nanolit: Nanocharacterization with lithium tracing for Li-ion batteries
• Minabatt: Micro-to Nanoscale Investigation of Interfacial Processes in Solid-State Batteries with Hybrid Electrolytes to Elucidate the Lithium Transport
• Soil3D: Elucidating the 3D chemical and physical architecture of soil microstructures by combining spectromicroscopic techniques and developing of novel computational approaches
• FLUO-GUT: Oral exposure and gut-targeted toxicity of PFOA and its precursor 8:2 FTOH under chronic stress: when high resolution chemical imaging bridges food toxicology